Seasonall 60 Capsules - Douglas Labs - 202126-60X

Vitamins 4 You

Product size: 60 Capsules
Manufacturer: Douglas Labs


Would you like to see Reviews of this product?

SeasonALL™ is a special combination of phytonutrients designed to support the immune response of the body to seasonal changes in the environment throughout the year. Ingredients such as Nettle leaf, bromelain, isoquercetin, Tinospora cordifolia, and elderberry help to maintain healthy immune function in response to the environment, including healthy mast cell function, cytokine balance and immune cell function. The special addition of Longvida® Optimized Curcumin with SLCP™ technology for enhanced curcumin absorption, works to modulate healthy cytokine levels.

Environmental agents, or antigens, are all around us indoors and outdoors and can trigger the normal immune response of the body to produce antibodies (IgE) in response to these foreign substances. IgE antibodies trigger mast cell and basophil activation. Mast cells are scattered throughout the connective tissue of the body and store a number of different chemical mediators, including histamine, interleukins, proteoglycans, and various enzymes which participate in the innate and adaptive immune responses. Specific herbal properties, flavones, and vitamins can help support a healthy immune system response to antigens.

TINOFEND® extract derived from Tinospora cordifolia used in Ayurvedic medicine contains polysaccharides and polyphenols that promote optimal immune health. This combination works through three actions; by regulating several immune mediators to stimulate the activity of white blood cells such as macrophages, by reducing the number of histamine-containing eosinophils, and lastly through the reduction of oxidative stress. A clinical study using Tinofend® extract in individuals with IgE antibodies that bind to high affinity receptors on mast cells and basophils, resulted in more favorable responses to antigens in the nasal passages, supporting the efficacy and tolerability of Tinospora cordifolia for immune support.

Curcumin modulates the body response to immune triggers by down-regulating the activity of cyclooxygenase-2 (COX-2), lipoxygenase, and inducible nitric oxide synthase (iNOS) enzymes and the production of cytokines and interleukins as measured in nasal homogenates. SeasonALL contains Longvida® Optimized Curcumin for enhanced absorption and increased bioavailability at a low dose. Longvida’s Solid Lipid Curcumin Particle (SLCP) Technology meets all three requirements for bioavailability - solubility, permeability, and stability as evidenced by therapeutic levels of free curcumin detected in the bloodstream and target tissues.

Nettles leaf, also called stinging nettle, offers a rich history of clinical and traditional use for maintaining healthy immune function in response to environmental triggers. Some researchers believe that stinging nettle might be beneficial for immune health due to the natural quercetin content.

Quercetin is thought to have regulatory and mast-cell stabilizing effects. In a Japanese study of mast cells from nasal mucosa of individuals with environmental triggers, quercetin was shown to help maintain a healthy immune response. Quercetin (aglycone) is currently among the most popular flavonoid supplements. It is not, however, the dominant form appearing in nature, and its bioavailability is poor. Quercetin glucosides, such as isoquercetin, occur naturally and have the same therapeutic effects in vivo as quercetin (aglycone), but with better bioavailability. Studies estimate that isoquercetin is 3–5 times more bioavailable than its natural form, and therefore it is anticipated that a lower dose of isoquercetin might reach comparable efficacy and be supplemented in a ratio of 1:5 relative to quercetin aglycone.

Bromelain, a proteolytic enzyme from pineapple, may thin nasal secretions and has been shown to be an effective enzyme to help regulate mucous production. This is in addition to bromelains proteolytic activity, which may promote the inhibition of prostaglandin biosynthesis and the initiation of prostaglandin E1 accumulation. Preliminary research suggests boswellic acids in Boswellia may help stabilize mast cells. The action of boswellic acids on 5-lipoxygenase (5-LO) inhibition leading to a decreased production of leukotrienes has received a high level of attention from the scientific community.

Studies using black elderberry fruit have indicated that it may have immuno-protective abilities, including support of a balanced production of cytokines. Vitamin D is a key factor linking innate and adaptive immunity due to the T-cells direct response to 1,25-dihydroxyvitamin D, which may be compromised under conditions of vitamin D insufficiency. The major role of Vitamin C is the protection of the immune cells against free radical damage. Vitamin C concentrations in the plasma and leukocytes rapidly decline during acute immune reactions and stress.

Usage of Douglas Labs Seasonall:
SeasonALL is a dietary supplement indicated for individuals that desire immune support during the seasonal changes in the environment.

Adults take 2 capsules daily with or without food. May increase to 2 capsules twice daily as needed for acute seasonal support . Please check with pediatrician prior to use for children.
Precautions / Interactions for Douglas Labs Seasonall:
Pregnant or lactating women should consult a physician prior to use. This product is contraindicated with immunosuppressive medications. Caution use in individuals with autoimmune disorders.
  2 Capsules:
Vitamin C (Ascorbic Acid) 50 mg
Vitamin D-3 (cholecalciferol) 500 IU
Proprietary blend 1025 mg
- Nettle leaf Extract (Urtica dioica L.)
- Tinofend® Extract (Tinospora cordifolia, stem)
- LONGVIDA® Optimized Curcumin Extract (from Curcuma longa root)
- Boswellia serrata Extract (dried gum)
- Elderberry fruit Extract (Sambucus nigra L.)(standardized to 25% total polyphenols)
- Isoquercetin
- Bromelain (yielding 5,000 m.c.u.)
Other Ingredients: Hydroxypropyl methylcellulose (capsule), phosphatidylcholine (from soy),
stearic acid, maltodextrin, ascorbyl palmitate, vegetable stearate, silica.

REVIEWS for Seasonall from Douglas Labs
There are currently no reviews for this supplement. Would you like to write one?
Vitamins 4 You Disclaimer: Manufacturers continually change product prices and specifications. We try our best to keep product descriptions up to date, although they do not necessarily reflect the latest information available from the manufacturer. No statements or information on this site have been evaluated by the Food and Drug Administration. No products are intended to diagnose, treat, cure or prevent any disease.

Douglas Labs Seasonall 60 Capsules



Wellness Letter Are you interested in learning more about products like the one on this page? We offer a monthly Wellness Newsletter that will inform you of recent developments in the field, new products from each of the manufacturers, and review some of the more recent research that is being done in the world of supplements.

Please click here to sign up for this newsletter.

HomeShopping CartBiotics ResearchDouglas LabsMetagenicsNutriwestPure EncapsulationsThorne Research

~ NEW ~

Pure Encapsulations: new product
PureDefense Chewables
5/20/2015 1:18:17 PM

PureDefense Chewables provides overall immune defense and upper respiratory health support in a great-tasting, chewable tablet.
  [ click here ]

Pure Encapsulations: new product
NeuroMood Pure Pack
5/18/2015 12:53:31 PM

Comprehensive daily packet providing vitamins, minerals, essential fatty acids, amino acids and curcumin for positive mood and emotional wellness
  [ click here ]

Biotics Research: New Product
NutriClear® Chocolate
5/8/2015 12:26:45 PM

NutriClear® Chocolate is used to support the normal detoxification pathways of the body, for metabolic clearing, as well as for healthy GI function.
  [ click here ]

Biotics Research: New Product
Mood Enhancer
5/6/2015 7:44:40 AM

Mood Enhancer was developed by Biotics Research to address serotonin need, and to supply important nutritional synergists to support healthy brain function.
  [ click here ]

Biotics Research: New Product
Cognitive Enhancer
5/5/2015 5:44:49 PM

Cognitive Enhancer from Biotics Research was developed to address our acetylcholine needs, and to give the brain the nutrients it requires to function at a higher level.
  [ click here ]

Biotics Research: New Product
4/29/2015 8:09:17 PM

The ingredients in this supplement are well researched and may be beneficial for the reduction of the symptoms related to migraine headaches.
  [ click here ]

Pure Encapsulations: new product
EmulsiSorb CoQ10 liquid 150 ml
1/7/2015 2:38:52 PM

Enhanced absorption emulsified coenzyme Q10 in a convenient liquid form
  [ click here ]

Pure Encapsulations: new product
1/7/2015 2:38:24 PM

Alpha-GPC is an important neurotransmitter and phospholipid precursor providing support for age-related decline in cognitive function, memory, and cerebrovascular health.
  [ click here ]

Pure Encapsulations: new product
O.N.E.™ Omega
1/7/2015 2:37:49 PM

Provides 1,000 mg triglyceride-form EPA and DHA per single softgel
  [ click here ]